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Synthesis of Cyclic Guanidines via Silver-Catalyzed Intramolecular Alkene Hydroamination Reactions of N-Allylguanidines

The silver-catalyzed hydroamination of tosyl-protected N-allylguanidines is described. These reactions provide substituted cyclic guanidines in high yields. The reactions are amenable to the construction of quaternary stereocenters as well as both monocyclic and bicyclic guanidine products.

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Xehetasun bibliografikoak
Argitaratua izan da:Org Lett
Egile Nagusiak: Garlets, Zachary J., Silvi, Mattia, Wolfe, John P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924592/
https://ncbi.nlm.nih.gov/pubmed/27181609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.6b00598
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