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Synthesis of Cyclic Guanidines via Pd-Catalyzed Alkene Carboamination

[Image: see text] A new approach to the synthesis of substituted 5-membered cyclic guanidines is described. Palladium-catalyzed alkene carboamination reactions between acyclic N-allyl guanidines and aryl or alkenyl halides provide these products in good yield. This method allows access to a number o...

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Autors principals: Zavesky, Blane P., Babij, Nicholas R., Fritz, Jonathan A., Wolfe, John P.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857308/
https://ncbi.nlm.nih.gov/pubmed/24147839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol402377y
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