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Synthesis of Substituted 2-Aminoimidazoles via Pd-Catalyzed Alkyne Carboamination Reactions. Application to the Synthesis of Preclathridine Natural Products

[Image: see text] A new method for the synthesis of 2-aminoimidazole products is described. The heterocyclic products are generated in good yields via Pd-catalyzed carboamination reactions of N-propargyl guanidines and aryl triflates. This methodology generates both a C–N and C–C bond during the ann...

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Main Authors: Zavesky, Blane P., Babij, Nicholas R., Wolfe, John P.
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2014
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4168774/
https://ncbi.nlm.nih.gov/pubmed/25198672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol502471x
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