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Synthesis of Cyclic Guanidines Bearing N-Arylsulfonyl and N-Cyano Protecting Groups via Pd-Catalyzed Alkene Carboamination Reactions

Palladium-catalyzed carboamination reactions of N-allylguanidines bearing cleavable N-cyano or N-arylsulfonyl protecting groups are described. The reactions afford cyclic guanidine products in good yield, and transformations of substrates bearing internal alkenes proceed with high diastereoselectivi...

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Enregistré dans:
Détails bibliographiques
Publié dans:Org Lett
Auteurs principaux: Peterson, Luke J., Luo, Jingyi, Wolfe, John P.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5674782/
https://ncbi.nlm.nih.gov/pubmed/28534637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.7b00946
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