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Synthesis of Cyclic Guanidines Bearing N-Arylsulfonyl and N-Cyano Protecting Groups via Pd-Catalyzed Alkene Carboamination Reactions

Palladium-catalyzed carboamination reactions of N-allylguanidines bearing cleavable N-cyano or N-arylsulfonyl protecting groups are described. The reactions afford cyclic guanidine products in good yield, and transformations of substrates bearing internal alkenes proceed with high diastereoselectivi...

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書目詳細資料
發表在:Org Lett
Main Authors: Peterson, Luke J., Luo, Jingyi, Wolfe, John P.
格式: Artigo
語言:Inglês
出版: 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5674782/
https://ncbi.nlm.nih.gov/pubmed/28534637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.7b00946
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