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Development of Enantioselective Pd-Catalyzed Alkene Carboalkoxylation Reactions for the Synthesis of Tetrahydrofurans
The Pd-catalyzed coupling of γ-hydroxyalkenes with aryl bromides affords enantiomerically enriched 2-(arylmethyl)tetrahydrofuran derivatives in good yield and up to 96:4 er. This transformation was achieved through the development of a new TADDOL/2-arylcyclohexanol-derived chiral phosphite ligand. T...
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| Yayımlandı: | Angew Chem Int Ed Engl |
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| Asıl Yazarlar: | , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4711365/ https://ncbi.nlm.nih.gov/pubmed/26366747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201506884 |
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