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Expression of Growth Hormone Genes in Transgenic Mice

Human or rat growth hormone (GH) genes have been introduced into all cells of a mouse by microinjection of fertilized eggs but they were not expressed under their own promoters. However, substitution of a mouse metallothionein (MT) promoter allowed expression and regulation comparable to that of the...

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Publicado en:Banbury Rep
Autores principales: Palmiter, Richard D., Hammer, Robert E., Brinster, Ralph L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1985
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922752/
https://ncbi.nlm.nih.gov/pubmed/27358506
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