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Expression of Growth Hormone Genes in Transgenic Mice

Human or rat growth hormone (GH) genes have been introduced into all cells of a mouse by microinjection of fertilized eggs but they were not expressed under their own promoters. However, substitution of a mouse metallothionein (MT) promoter allowed expression and regulation comparable to that of the...

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Publicat a:Banbury Rep
Autors principals: Palmiter, Richard D., Hammer, Robert E., Brinster, Ralph L.
Format: Artigo
Idioma:Inglês
Publicat: 1985
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922752/
https://ncbi.nlm.nih.gov/pubmed/27358506
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