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Expression of a microinjected immunoglobulin gene in the spleen of transgenic mice

Transgenic mice were produced by microinjection of a rearranged, functional immunoglobulin κ gene into fertilized mouse eggs and implantation of the microinjected embryos into foster mothers. Mice that integrated the injected gene were mated and the DNA, RNA and serum κ chains of their offspring wer...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Brinster, Ralph L., Ritchie, Kindred A., Hammer, Robert E., O’Brien, Rebecca L., Arp, Benjamin, Storb, Ursula
Formato: Artigo
Idioma:Inglês
Publicado em: 1983
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4883675/
https://ncbi.nlm.nih.gov/pubmed/6417544
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