Expression of human beta-globin genes in transgenic mice: effects of a flanking metallothionein-human growth hormone fusion gene.

In an attempt to place a human beta-globin gene in an open chromatin domain regardless of its site of integration in the mouse genome, we microinjected into fertilized mouse eggs a construct in which the human beta-globin gene and a mouse metallothionein-human growth hormone fusion gene were juxtapo...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Townes, T M, Chen, H Y, Lingrel, J B, Palmiter, R D, Brinster, R L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1985
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC366915/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3018541/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.5.8.1977-1983.1985
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