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Expression of human beta-globin genes in transgenic mice: effects of a flanking metallothionein-human growth hormone fusion gene.

In an attempt to place a human beta-globin gene in an open chromatin domain regardless of its site of integration in the mouse genome, we microinjected into fertilized mouse eggs a construct in which the human beta-globin gene and a mouse metallothionein-human growth hormone fusion gene were juxtapo...

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Библиографические подробности
Главные авторы: Townes, T M, Chen, H Y, Lingrel, J B, Palmiter, R D, Brinster, R L
Формат: Artigo
Язык:Inglês
Опубликовано: 1985
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC366915/
https://ncbi.nlm.nih.gov/pubmed/3018541
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