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Eukaryotic Genome Instability in Light of Asymmetric DNA Replication

The eukaryotic nuclear genome is replicated asymmetrically, with the leading strand replicated continuously and the lagging strand replicated as discontinuous Okazaki fragments that are subsequently joined. Both strands are replicated with high fidelity, but the processes used to achieve high fideli...

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Detaylı Bibliyografya
Yayımlandı:Crit Rev Biochem Mol Biol
Asıl Yazarlar: Lujan, Scott A., Williams, Jessica S., Kunkel, Thomas A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922258/
https://ncbi.nlm.nih.gov/pubmed/26822554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10409238.2015.1117055
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