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Eukaryotic Genome Instability in Light of Asymmetric DNA Replication
The eukaryotic nuclear genome is replicated asymmetrically, with the leading strand replicated continuously and the lagging strand replicated as discontinuous Okazaki fragments that are subsequently joined. Both strands are replicated with high fidelity, but the processes used to achieve high fideli...
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| Pubblicato in: | Crit Rev Biochem Mol Biol |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4922258/ https://ncbi.nlm.nih.gov/pubmed/26822554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10409238.2015.1117055 |
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