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Genome-wide model for the normal eukaryotic DNA replication fork
To investigate DNA replication enzymology across the nuclear genome of budding yeast, deep sequencing was used to establish the pattern of uncorrected replication errors generated by an asymmetric mutator variant of DNA polymerase δ (Pol δ). Sequencing of 16 genomes identified 1,206-bp substitutions...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2955150/ https://ncbi.nlm.nih.gov/pubmed/20876092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010178107 |
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