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Genome-wide model for the normal eukaryotic DNA replication fork

To investigate DNA replication enzymology across the nuclear genome of budding yeast, deep sequencing was used to establish the pattern of uncorrected replication errors generated by an asymmetric mutator variant of DNA polymerase δ (Pol δ). Sequencing of 16 genomes identified 1,206-bp substitutions...

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Xehetasun bibliografikoak
Egile Nagusiak: Larrea, Andres A., Lujan, Scott A., McElhinny, Stephanie A. Nick, Mieczkowski, Piotr A., Resnick, Michael A., Gordenin, Dmitry A., Kunkel, Thomas A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955150/
https://ncbi.nlm.nih.gov/pubmed/20876092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010178107
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