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Dividing the workload at a eukaryotic replication fork

Efficient and accurate replication of the eukaryotic nuclear genome requires DNA polymerases (Pols) α, δ and ε. In all current replication fork models, polymerase α initiates replication. However, several models have been proposed for the roles of Pol δ and Pol ε in subsequent chain elongation and t...

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Hlavní autoři: Kunkel, Thomas A., Burgers, Peter M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665207/
https://ncbi.nlm.nih.gov/pubmed/18824354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2008.08.005
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