New insights into salvianolic acid A action: Regulation of the TXNIP/NLRP3 and TXNIP/ChREBP pathways ameliorates HFD-induced NAFLD in rats

Salvianolic acid A (SalA), one of the most efficacious polyphenol compounds extracted from Radix Salvia miltiorrhiza (Danshen), has been shown to possess many potential pharmacological activities. This study aimed to investigate whether SalA has hepatoprotective effects against high-fat diet (HFD)-i...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ding, Chunchun, Zhao, Yan, Shi, Xue, Zhang, Ning, Zu, Guo, Li, Zhenlu, Zhou, Junjun, Gao, Dongyan, Lv, Li, Tian, Xiaofeng, Yao, Jihong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922017/
https://ncbi.nlm.nih.gov/pubmed/27345365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28734
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