Intestinal, but not hepatic, ChREBP is required for fructose tolerance

Increased sugar consumption is a risk factor for the metabolic syndrome including obesity, hypertriglyceridemia, insulin resistance, diabetes, and nonalcoholic fatty liver disease (NAFLD). Carbohydrate responsive element–binding protein (ChREBP) is a transcription factor that responds to sugar consu...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Kim, MiSung, Astapova, Inna I., Flier, Sarah N., Hannou, Sarah A., Doridot, Ludivine, Sargsyan, Ashot, Kou, Henry H., Fowler, Alan J., Liang, Guosheng, Herman, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752301/
https://ncbi.nlm.nih.gov/pubmed/29263303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.96703
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