A critical role for ChREBP-mediated FGF21 secretion in hepatic fructose metabolism

OBJECTIVE: Increased fructose consumption is a contributor to the burgeoning epidemic of non-alcoholic fatty liver disease (NAFLD). Recent evidence indicates that the metabolic hormone FGF21 is regulated by fructose consumption in humans and rodents and may play a functional role in this nutritional...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Fisher, ffolliott M., Kim, MiSung, Doridot, Ludivine, Cunniff, Jeremy C., Parker, Thomas S., Levine, Daniel M., Hellerstein, Marc K., Hudgins, Lisa C., Maratos-Flier, Eleftheria, Herman, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5220398/
https://ncbi.nlm.nih.gov/pubmed/28123933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.11.008
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