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Cas-Database: web-based genome-wide guide RNA library design for gene knockout screens using CRISPR-Cas9
Motivation: CRISPR-derived RNA guided endonucleases (RGENs) have been widely used for both gene knockout and knock-in at the level of single or multiple genes. RGENs are now available for forward genetic screens at genome scale, but single guide RNA (sgRNA) selection at this scale is difficult. Resu...
שמור ב:
| הוצא לאור ב: | Bioinformatics |
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| Main Authors: | , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Oxford University Press
2016
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4920116/ https://ncbi.nlm.nih.gov/pubmed/27153724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw103 |
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