Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases

Summary: The Type II clustered regularly interspaced short palindromic repeats (CRISPR)/Cas system is an adaptive immune response in prokaryotes, protecting host cells against invading phages or plasmids by cleaving these foreign DNA species in a targeted manner. CRISPR/Cas-derived RNA-guided engine...

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Detaylı Bibliyografya
Asıl Yazarlar: Bae, Sangsu, Park, Jeongbin, Kim, Jin-Soo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2014
Konular:
Applications Notes
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016707/
https://ncbi.nlm.nih.gov/pubmed/24463181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu048
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