Lataa...
Structural roles of guide RNAs in the nuclease activity of Cas9 endonuclease
The type II CRISPR-associated protein Cas9 recognizes and cleaves target DNA with the help of two guide RNAs (gRNAs; tracrRNA and crRNA). However, the detailed mechanisms and kinetics of these gRNAs in the Cas9 nuclease activity are unclear. Here, we investigate the structural roles of gRNAs in the...
Tallennettuna:
| Julkaisussa: | Nat Commun |
|---|---|
| Päätekijät: | , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Nature Publishing Group
2016
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5097132/ https://ncbi.nlm.nih.gov/pubmed/27804953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13350 |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|