Cargando...

Cas-Database: web-based genome-wide guide RNA library design for gene knockout screens using CRISPR-Cas9

Motivation: CRISPR-derived RNA guided endonucleases (RGENs) have been widely used for both gene knockout and knock-in at the level of single or multiple genes. RGENs are now available for forward genetic screens at genome scale, but single guide RNA (sgRNA) selection at this scale is difficult. Resu...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Bioinformatics
Main Authors: Park, Jeongbin, Kim, Jin-Soo, Bae, Sangsu
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4920116/
https://ncbi.nlm.nih.gov/pubmed/27153724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw103
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!