Multi-epitope Models Explain How Pre-existing Antibodies Affect the Generation of Broadly Protective Responses to Influenza

The development of next-generation influenza vaccines that elicit strain-transcendent immunity against both seasonal and pandemic viruses is a key public health goal. Targeting the evolutionarily conserved epitopes on the stem of influenza’s major surface molecule, hemagglutinin, is an appealing pro...

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Detaylı Bibliyografya
Yayımlandı:PLoS Pathog
Asıl Yazarlar: Zarnitsyna, Veronika I., Lavine, Jennie, Ellebedy, Ali, Ahmed, Rafi, Antia, Rustom
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918916/
https://ncbi.nlm.nih.gov/pubmed/27336297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005692
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