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Masking of antigenic epitopes by antibodies shapes the humoral immune response to influenza

The immune responses to influenza, a virus that exhibits strain variation, show complex dynamics where prior immunity shapes the response to the subsequent infecting strains. Original antigenic sin (OAS) describes the observation that antibodies to the first encountered influenza strain, specificall...

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Bibliografiske detaljer
Udgivet i:Philos Trans R Soc Lond B Biol Sci
Main Authors: Zarnitsyna, Veronika I., Ellebedy, Ali H., Davis, Carl, Jacob, Joshy, Ahmed, Rafi, Antia, Rustom
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528424/
https://ncbi.nlm.nih.gov/pubmed/26194761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2014.0248
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