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Masking of antigenic epitopes by antibodies shapes the humoral immune response to influenza

The immune responses to influenza, a virus that exhibits strain variation, show complex dynamics where prior immunity shapes the response to the subsequent infecting strains. Original antigenic sin (OAS) describes the observation that antibodies to the first encountered influenza strain, specificall...

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Detalles Bibliográficos
Publicado en:Philos Trans R Soc Lond B Biol Sci
Autores principales: Zarnitsyna, Veronika I., Ellebedy, Ali H., Davis, Carl, Jacob, Joshy, Ahmed, Rafi, Antia, Rustom
Formato: Artigo
Lenguaje:Inglês
Publicado: The Royal Society 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528424/
https://ncbi.nlm.nih.gov/pubmed/26194761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2014.0248
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