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Masking of antigenic epitopes by antibodies shapes the humoral immune response to influenza

The immune responses to influenza, a virus that exhibits strain variation, show complex dynamics where prior immunity shapes the response to the subsequent infecting strains. Original antigenic sin (OAS) describes the observation that antibodies to the first encountered influenza strain, specificall...

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Detalhes bibliográficos
Publicado no:Philos Trans R Soc Lond B Biol Sci
Main Authors: Zarnitsyna, Veronika I., Ellebedy, Ali H., Davis, Carl, Jacob, Joshy, Ahmed, Rafi, Antia, Rustom
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528424/
https://ncbi.nlm.nih.gov/pubmed/26194761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2014.0248
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