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How sticky should a virus be? The impact of virus binding and release on transmission fitness using influenza as an example

Budding viruses face a trade-off: virions need to efficiently attach to and enter uninfected cells while newly generated virions need to efficiently detach from infected cells. The right balance between attachment and detachment—the right amount of stickiness—is needed for maximum fitness. Here, we...

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Detalhes bibliográficos
Main Authors: Handel, Andreas, Akin, Victoria, Pilyugin, Sergei S., Zarnitsyna, Veronika, Antia, Rustom
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899878/
https://ncbi.nlm.nih.gov/pubmed/24430126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2013.1083
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