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How sticky should a virus be? The impact of virus binding and release on transmission fitness using influenza as an example

Budding viruses face a trade-off: virions need to efficiently attach to and enter uninfected cells while newly generated virions need to efficiently detach from infected cells. The right balance between attachment and detachment—the right amount of stickiness—is needed for maximum fitness. Here, we...

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Bibliographische Detailangaben
Hauptverfasser: Handel, Andreas, Akin, Victoria, Pilyugin, Sergei S., Zarnitsyna, Veronika, Antia, Rustom
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Royal Society 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899878/
https://ncbi.nlm.nih.gov/pubmed/24430126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2013.1083
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