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A Simple Mathematical Model Helps To Explain the Immunodominance of CD8 T Cells in Influenza A Virus Infections

Understanding immunodominance, the phenomenon of epitope-specific T cells expanding in an often distinctly hierarchical fashion, is important for the design of T-cell-based intervention strategies. Several recent studies have investigated immunodominance of H-2D(b)-restricted CD8(+) T cells specific...

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Hlavní autoři: Handel, Andreas, Antia, Rustom
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519595/
https://ncbi.nlm.nih.gov/pubmed/18550672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00653-08
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