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Consequences of Immunodominant Epitope Deletion for Minor Influenza Virus-Specific CD8(+)-T-Cell Responses
The extent to which CD8(+) T cells specific for other antigens expand to compensate for the mutational loss of the prominent D(b)NP(366) and D(b)PA(224) epitopes has been investigated using H1N1 and H3N2 influenza A viruses modified by reverse genetics. Significantly increased numbers of CD8(+) K(b)...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Microbiology
2005
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1061524/ https://ncbi.nlm.nih.gov/pubmed/15767433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.7.4329-4339.2005 |
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