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Masking of antigenic epitopes by antibodies shapes the humoral immune response to influenza

The immune responses to influenza, a virus that exhibits strain variation, show complex dynamics where prior immunity shapes the response to the subsequent infecting strains. Original antigenic sin (OAS) describes the observation that antibodies to the first encountered influenza strain, specificall...

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Bibliographische Detailangaben
Veröffentlicht in:Philos Trans R Soc Lond B Biol Sci
Hauptverfasser: Zarnitsyna, Veronika I., Ellebedy, Ali H., Davis, Carl, Jacob, Joshy, Ahmed, Rafi, Antia, Rustom
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Royal Society 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528424/
https://ncbi.nlm.nih.gov/pubmed/26194761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2014.0248
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