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Synthesis and Biological Evaluation of Manzamine Analogues

The synthesis and biological evaluation of a series of analogues of manzamine A, representing partial structures of the pentacyclic ABCDE diamine core, is described. All new compounds were screened against Plasmodium falciparum and demonstrated attenuated antimalarial activity relative to that of ma...

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Publicat a:Org Lett
Autors principals: Winkler, Jeffrey D., Londregan, Allyn T., Ragains, Justin R., Hamann, Mark T.
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918913/
https://ncbi.nlm.nih.gov/pubmed/16836417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol061320b
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