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Synthesis and Biological Evaluation of Manzamine Analogues

The synthesis and biological evaluation of a series of analogues of manzamine A, representing partial structures of the pentacyclic ABCDE diamine core, is described. All new compounds were screened against Plasmodium falciparum and demonstrated attenuated antimalarial activity relative to that of ma...

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Bibliografske podrobnosti
izdano v:Org Lett
Main Authors: Winkler, Jeffrey D., Londregan, Allyn T., Ragains, Justin R., Hamann, Mark T.
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918913/
https://ncbi.nlm.nih.gov/pubmed/16836417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol061320b
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