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Synthesis and Biological Evaluation of Manzamine Analogues

The synthesis and biological evaluation of a series of analogues of manzamine A, representing partial structures of the pentacyclic ABCDE diamine core, is described. All new compounds were screened against Plasmodium falciparum and demonstrated attenuated antimalarial activity relative to that of ma...

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Detalhes bibliográficos
Publicado no:Org Lett
Main Authors: Winkler, Jeffrey D., Londregan, Allyn T., Ragains, Justin R., Hamann, Mark T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918913/
https://ncbi.nlm.nih.gov/pubmed/16836417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol061320b
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