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Synthesis and Biological Evaluation of Manzamine Analogues

The synthesis and biological evaluation of a series of analogues of manzamine A, representing partial structures of the pentacyclic ABCDE diamine core, is described. All new compounds were screened against Plasmodium falciparum and demonstrated attenuated antimalarial activity relative to that of ma...

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Publicado en:Org Lett
Autores principales: Winkler, Jeffrey D., Londregan, Allyn T., Ragains, Justin R., Hamann, Mark T.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918913/
https://ncbi.nlm.nih.gov/pubmed/16836417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol061320b
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