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Does a Sentinel or a Subset of Short Telomeres Determine Replicative Senescence?
The proliferative life span of human cells is limited by telomere shortening, but the specific telomeres responsible for determining the onset of senescence have not been adequately determined. We here identify the shortest telomeres by the frequency of signal-free ends after in situ hybridization w...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The American Society for Cell Biology
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC491830/ https://ncbi.nlm.nih.gov/pubmed/15181152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-03-0207 |
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