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CD40 stimulation obviates innate sensors and drives T cell immunity in cancer

Cancer immunotherapies are more effective in tumors with robust T cell infiltrates, but mechanisms to convert T cell-devoid tumors with active immunosuppression to those capable of recruiting T cells remain incompletely understood. Here, using genetically engineered mouse models of pancreatic ductal...

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Bibliographic Details
Published in:Cell Rep
Main Authors: Byrne, Katelyn T., Vonderheide, Robert H.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917417/
https://ncbi.nlm.nih.gov/pubmed/27292635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.05.058
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