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Sufficiency of CD40 activation and immune checkpoint blockade for T cell priming and tumor immunity

Innate immune receptors such as toll-like receptors (TLRs) provide critical molecular links between innate cells and adaptive immune responses. Here, we studied the CD40 pathway as an alternative bridge between dendritic cells (DCs) and adaptive immunity in cancer. Using an experimental design free...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Morrison, Alexander H., Diamond, Mark S., Hay, Ceire A., Byrne, Katelyn T., Vonderheide, Robert H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7149500/
https://ncbi.nlm.nih.gov/pubmed/32213589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1918971117
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