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Cancer immunotherapy: activating innate and adaptive immunity through CD40 agonists

INTRODUCTION: CD40 is a promising therapeutic target for cancer immunotherapy. In patients with advanced solid malignancies, CD40 agonists have demonstrated some anti-tumor activity and a manageable toxicity profile. A 2(nd) generation of CD40 agonists has now been designed with optimized Fc recepto...

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Detalhes bibliográficos
Publicado no:Expert Rev Anticancer Ther
Main Authors: Beatty, Gregory L., Li, Yan, Long, Kristen B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533512/
https://ncbi.nlm.nih.gov/pubmed/27927088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14737140.2017.1270208
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