Nalaganje...
Directed evolution of RebH for catalyst-controlled halogenation of indole C–H bonds
RebH variants capable of chlorinating substituted indoles ortho-, meta-, and para- to the indole nitrogen were evolved by directly screening for altered selectivity on deuterium-substituted probe substrates using mass spectrometry. This systematic approach allowed for rapid accumulation of beneficia...
Shranjeno v:
| izdano v: | Chem Sci |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Royal Society of Chemistry
2016
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4917012/ https://ncbi.nlm.nih.gov/pubmed/27347367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc04680g |
| Oznake: |
Označite
Brez oznak, prvi označite!
|