Caricamento...
Directed evolution of RebH for catalyst-controlled halogenation of indole C–H bonds
RebH variants capable of chlorinating substituted indoles ortho-, meta-, and para- to the indole nitrogen were evolved by directly screening for altered selectivity on deuterium-substituted probe substrates using mass spectrometry. This systematic approach allowed for rapid accumulation of beneficia...
Salvato in:
| Pubblicato in: | Chem Sci |
|---|---|
| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Royal Society of Chemistry
2016
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4917012/ https://ncbi.nlm.nih.gov/pubmed/27347367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc04680g |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|