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The eukaryotic CMG helicase pumpjack and integration into the replisome

The eukaryotic replisome is α multiprotein machine that contains DNA polymerases, sliding clamps, helicase, and primase along with several factors that participate in cell cycle and checkpoint control. The detailed structure of the 11-subunit CMG helicase (Cdc45/Mcm2-7/GINS) has been solved recently...

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Publicat a:Nucleus
Autors principals: Sun, Jingchuan, Yuan, Zuanning, Georgescu, Roxanna, Li, Huilin, O'Donnell, Mike
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4916876/
https://ncbi.nlm.nih.gov/pubmed/27310307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2016.1174800
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