Neutralizing antibody affords comparable protection against vaginal and rectal SHIV challenge in macaques

OBJECTIVE: Passive administration of broadly neutralizing antibodies (bnAbs) has been shown to protect against both vaginal and rectal challenge in the SHIV/macaque model of HIV transmission. However, the relative efficacy of antibody against the two modes of exposure is unknown and, given differenc...

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Dettagli Bibliografici
Pubblicato in:AIDS
Autori principali: MOLDT, Brian, LE, Khoa, CARNATHAN, Diane G., WHITNEY, James B., SCHULTZ, Niccole, LEWIS, Mark G., BORDUCCHI, Erica, SMITH, Kaitlin, MACKEL, Joseph J., SWEAT, Shelby L., HODGES, Andrew P., GODZIK, Adam, PARREN, Paul W. H. I., SILVESTRI, Guido, BAROUCH, Dan H., BURTON, Dennis R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915739/
https://ncbi.nlm.nih.gov/pubmed/27243773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000001102
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