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Neutralizing antibody affords comparable protection against vaginal and rectal SHIV challenge in macaques

OBJECTIVE: Passive administration of broadly neutralizing antibodies (bnAbs) has been shown to protect against both vaginal and rectal challenge in the SHIV/macaque model of HIV transmission. However, the relative efficacy of antibody against the two modes of exposure is unknown and, given differenc...

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Vydáno v:	AIDS
Hlavní autoři:	MOLDT, Brian, LE, Khoa, CARNATHAN, Diane G., WHITNEY, James B., SCHULTZ, Niccole, LEWIS, Mark G., BORDUCCHI, Erica, SMITH, Kaitlin, MACKEL, Joseph J., SWEAT, Shelby L., HODGES, Andrew P., GODZIK, Adam, PARREN, Paul W. H. I., SILVESTRI, Guido, BAROUCH, Dan H., BURTON, Dennis R.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	2016
Témata:	Article
On-line přístup:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4915739/ https://ncbi.nlm.nih.gov/pubmed/27243773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000001102
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Neutralizing antibody affords comparable protection against vaginal and rectal SHIV challenge in macaques

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