Neutralizing antibody affords comparable protection against vaginal and rectal SHIV challenge in macaques

OBJECTIVE: Passive administration of broadly neutralizing antibodies (bnAbs) has been shown to protect against both vaginal and rectal challenge in the SHIV/macaque model of HIV transmission. However, the relative efficacy of antibody against the two modes of exposure is unknown and, given differenc...

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Veröffentlicht in:AIDS
Hauptverfasser: MOLDT, Brian, LE, Khoa, CARNATHAN, Diane G., WHITNEY, James B., SCHULTZ, Niccole, LEWIS, Mark G., BORDUCCHI, Erica, SMITH, Kaitlin, MACKEL, Joseph J., SWEAT, Shelby L., HODGES, Andrew P., GODZIK, Adam, PARREN, Paul W. H. I., SILVESTRI, Guido, BAROUCH, Dan H., BURTON, Dennis R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915739/
https://ncbi.nlm.nih.gov/pubmed/27243773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000001102
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