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Neutralizing antibody affords comparable protection against vaginal and rectal SHIV challenge in macaques

OBJECTIVE: Passive administration of broadly neutralizing antibodies (bnAbs) has been shown to protect against both vaginal and rectal challenge in the SHIV/macaque model of HIV transmission. However, the relative efficacy of antibody against the two modes of exposure is unknown and, given differenc...

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Bibliografske podrobnosti
izdano v:	AIDS
Main Authors:	MOLDT, Brian, LE, Khoa, CARNATHAN, Diane G., WHITNEY, James B., SCHULTZ, Niccole, LEWIS, Mark G., BORDUCCHI, Erica, SMITH, Kaitlin, MACKEL, Joseph J., SWEAT, Shelby L., HODGES, Andrew P., GODZIK, Adam, PARREN, Paul W. H. I., SILVESTRI, Guido, BAROUCH, Dan H., BURTON, Dennis R.
Format:	Artigo
Jezik:	Inglês
Izdano:	2016
Teme:	Article
Online dostop:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4915739/ https://ncbi.nlm.nih.gov/pubmed/27243773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000001102
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Neutralizing antibody affords comparable protection against vaginal and rectal SHIV challenge in macaques

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