Prevention of vaginal SHIV transmission in macaques by a live recombinant Lactobacillus

Most HIV transmission in women occurs through the cervicovaginal mucosa, which is coated by a bacterial biofilm including Lactobacillus. This commensal bacterium plays a role in maintaining healthy mucosa and can be genetically engineered to produce anti-viral peptides. Here, we report a 63% reducti...

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Main Authors: Lagenaur, Laurel A, Sanders-Beer, Brigitte E, Brichacek, Beda, Pal, Ranajit, Liu, Xiaowen, Liu, Yang, Yu, Rosa, Venzon, David, Lee, Peter P, Hamer, Dean H
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433722/
https://ncbi.nlm.nih.gov/pubmed/21734653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2011.30
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