Therapeutic antibody engineering: Current and future advances driving the strongest growth area in the pharmaceutical industry

Por Parren, Paul W.H.I., Lugovskoy, Alexey A.
Publicado em 2013

Fab-arm exchange: What’s in a name?

Por Schuurman, Janine, Labrijn, Aran F., Parren, Paul W.H.I.
Publicado em 2012

Changes to International Nonproprietary Names for antibody therapeutics 2017 and beyond: of mice, men and more

Por Parren, Paul W. H. I., Carter, Paul J., Plückthun, Andreas
Publicado no MAbs (2017)

Genetic Subtypes, Humoral Immunity, and Human Immunodeficiency Virus Type 1 Vaccine Development

Por Moore, John P., Parren, Paul W. H. I., Burton, Dennis R.
Publicado em 2001

High-Throughput Screening for Internalizing Antibodies by Homogeneous Fluorescence Imaging of a pH-Activated Probe

Por Riedl, Thilo, van Boxtel, Egon, Bosch, Martijn, Parren, Paul W. H. I., Gerritsen, Arnout F.
Publicado no J Biomol Screen (2016)

Pre- and Postexposure Prophylaxis of Ebola Virus Infection in an Animal Model by Passive Transfer of a Neutralizing Human Antibody

Por Parren, Paul W. H. I., Geisbert, Tom W., Maruyama, Toshiaki, Jahrling, Peter B., Burton, Dennis R.
Publicado em 2002

Fine Mapping of the Interaction of Neutralizing and Nonneutralizing Monoclonal Antibodies with the CD4 Binding Site of Human Immunodeficiency Virus Type 1 gp120

Por Pantophlet, Ralph, Ollmann Saphire, Erica, Poignard, Pascal, Parren, Paul W. H. I., Wilson, Ian A., Burton, Dennis R.
Publicado em 2003

Effector Function Activities of a Panel of Mutants of a Broadly Neutralizing Antibody against Human Immunodeficiency Virus Type 1

Por Hezareh, Marjan, Hessell, Ann J., Jensen, Richard C., van de Winkel, Jan G. J., Parren, Paul W. H. I.
Publicado em 2001

Neutralization Synergy of Human Immunodeficiency Virus Type 1 Primary Isolates by Cocktails of Broadly Neutralizing Antibodies

Por Zwick, Michael B., Wang, Meng, Poignard, Pascal, Stiegler, Gabriela, Katinger, Hermann, Burton, Dennis R., Parren, Paul W. H. I.
Publicado em 2001

Neutralizing Human Fab Fragments against Measles Virus Recovered by Phage Display

Por de Carvalho Nicacio, Cristina, Williamson, R. Anthony, Parren, Paul W. H. I., Lundkvist, Åke, Burton, Dennis R., Björling, Ewa
Publicado em 2002

Novel human antibody therapeutics: The age of the Umabs

Por Ruuls, Sigrid R, van Bueren, Jeroen J Lammerts, van de Winkel, Jan G J, Parren, Paul W H I
Publicado em 2008

Neutralization of IL-8 Prevents the Induction of Dermatologic Adverse Events Associated with the Inhibition of Epidermal Growth Factor Receptor

Por Bangsgaard, Nannie, Houtkamp, Mischa, Schuurhuis, Danita H., Parren, Paul W. H. I., Baadsgaard, Ole, Niessen, Hans W. M., Skov, Lone
Publicado em 2012

Enhancing Accuracy in Molecular Weight Determination of Highly Heterogeneously Glycosylated Proteins by Native Tandem Mass Spectrometry

Por Wang, Guanbo, de Jong, Rob N., van den Bremer, Ewald T. J., Parren, Paul W. H. I., Heck, Albert J. R.
Publicado no Anal Chem (2017)

Neutralization of Human Immunodeficiency Virus Type 1 by Antibody to gp120 Is Determined Primarily by Occupancy of Sites on the Virion Irrespective of Epitope Specificity

Por Parren, Paul W. H. I., Mondor, Isabelle, Naniche, Denise, Ditzel, Henrik J., Klasse, P. J., Burton, Dennis R., Sattentau, Quentin J.
Publicado em 1998

Determinants of Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Activation by Soluble CD4 and Monoclonal Antibodies

Por Sullivan, Nancy, Sun, Ying, Binley, James, Lee, Juliette, Barbas, Carlos F., Parren, Paul W. H. I., Burton, Dennis R., Sodroski, Joseph
Publicado em 1998

Assorted Mutations in the Envelope Gene of Simian Immunodeficiency Virus Lead to Loss of Neutralization Resistance against Antibodies Representing a Broad Spectrum of Specificities

Por Johnson, Welkin E., Sanford, Hannah, Schwall, Linda, Burton, Dennis R., Parren, Paul W. H. I., Robinson, James E., Desrosiers, Ronald C.
Publicado em 2003

Inhibition of Virus Attachment to CD4(+) Target Cells Is a Major Mechanism of T Cell Line–adapted HIV-1 Neutralization

Por Ugolini, Sophie, Mondor, Isabelle, Parren, Paul W.H.I., Burton, Dennis R., Tilley, Shermaine A., Klasse, Per Johan, Sattentau, Quentin J.
Publicado em 1997

Antibody Neutralization-Resistant Primary Isolates of Human Immunodeficiency Virus Type 1

Por Parren, Paul W. H. I., Wang, Meng, Trkola, Alexandra, Binley, James M., Purtscher, Martin, Katinger, Hermann, Moore, John P., Burton, Dennis R.
Publicado em 1998

Heterogeneity of Envelope Molecules Expressed on Primary Human Immunodeficiency Virus Type 1 Particles as Probed by the Binding of Neutralizing and Nonneutralizing Antibodies

Por Poignard, Pascal, Moulard, Maxime, Golez, Edwin, Vivona, Veronique, Franti, Michael, Venturini, Sara, Wang, Meng, Parren, Paul W. H. I., Burton, Dennis R.
Publicado em 2003

Simian Immunodeficiency Virus (SIV) Envelope-Specific Fabs with High-Level Homologous Neutralizing Activity: Recovery from a Long-Term-Nonprogressor SIV-Infected Macaque

Por Glamann, Joakim, Burton, Dennis R., Parren, Paul W. H. I., Ditzel, Henrik J., Kent, Karen A., Arnold, Caroline, Montefiori, David, Hirsch, Vanessa M.
Publicado em 1998