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Negative autoregulation of BMP dependent transcription by SIN3B splicing reveals a role for RBM39

BMP signalling is negatively autoregulated by several genes including SMAD6, Noggin and Gremlin, and autoregulators are possible targets for enhancing BMP signalling in disorders such as fibrosis and pulmonary hypertension. To identify novel negative regulators of BMP signalling, we used siRNA scree...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Faherty, Noel, Benson, Matthew, Sharma, Eshita, Lee, Angela, Howarth, Alison, Lockstone, Helen, Ebner, Daniel, Bhattacharya, Shoumo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914931/
https://ncbi.nlm.nih.gov/pubmed/27324164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28210
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