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Negative autoregulation of BMP dependent transcription by SIN3B splicing reveals a role for RBM39

BMP signalling is negatively autoregulated by several genes including SMAD6, Noggin and Gremlin, and autoregulators are possible targets for enhancing BMP signalling in disorders such as fibrosis and pulmonary hypertension. To identify novel negative regulators of BMP signalling, we used siRNA scree...

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Foilsithe in:Sci Rep
Main Authors: Faherty, Noel, Benson, Matthew, Sharma, Eshita, Lee, Angela, Howarth, Alison, Lockstone, Helen, Ebner, Daniel, Bhattacharya, Shoumo
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914931/
https://ncbi.nlm.nih.gov/pubmed/27324164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28210
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