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Autoregulation of RBM10 and cross-regulation of RBM10/RBM5 via alternative splicing-coupled nonsense-mediated decay

Mutations in the spliceosomal RNA binding protein RBM10 cause TARP syndrome and are frequently observed in lung adenocarcinoma (LUAD). We have previously shown that RBM10 enhances exon skipping of its target genes, including its paralog RBM5. Here, we report that RBM10 negatively regulates its own m...

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書目詳細資料
發表在:Nucleic Acids Res
Main Authors: Sun, Yue, Bao, Yufang, Han, Wenjian, Song, Fan, Shen, Xianfeng, Zhao, Jiawei, Zuo, Ji, Saffen, David, Chen, Wei, Wang, Zefeng, You, Xintian, Wang, Yongbo
格式: Artigo
語言:Inglês
出版: Oxford University Press 2017
主題:
RNA
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737846/
https://ncbi.nlm.nih.gov/pubmed/28586478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx508
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