RNA binding motif protein 10 suppresses lung cancer progression by controlling alternative splicing of eukaryotic translation initiation factor 4H

BACKGROUND: RNA splicing defects are emerging molecular hallmarks of cancer. The gene encoding splicing factor RNA binding motif protein 10 (RBM10) has been found frequently mutated in various types of cancer, particularly lung adenocarcinoma (LUAD), but how RBM10 affects cancer pathogenesis remains...

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Dades bibliogràfiques
Publicat a:EBioMedicine
Autors principals: Zhang, Sirui, Bao, Yufang, Shen, Xianfeng, Pan, Yunjian, Sun, Yue, Xiao, Man, Chen, Kexuan, Wei, Huanhuan, Zuo, Ji, Saffen, David, Zong, Wei-Xing, Sun, Yihua, Wang, Zefeng, Wang, Yongbo
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
Matèries:
Research paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7585942/
https://ncbi.nlm.nih.gov/pubmed/33130397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.103067
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