RNA binding motif protein 10 suppresses lung cancer progression by controlling alternative splicing of eukaryotic translation initiation factor 4H

BACKGROUND: RNA splicing defects are emerging molecular hallmarks of cancer. The gene encoding splicing factor RNA binding motif protein 10 (RBM10) has been found frequently mutated in various types of cancer, particularly lung adenocarcinoma (LUAD), but how RBM10 affects cancer pathogenesis remains...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Zhang, Sirui, Bao, Yufang, Shen, Xianfeng, Pan, Yunjian, Sun, Yue, Xiao, Man, Chen, Kexuan, Wei, Huanhuan, Zuo, Ji, Saffen, David, Zong, Wei-Xing, Sun, Yihua, Wang, Zefeng, Wang, Yongbo
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7585942/
https://ncbi.nlm.nih.gov/pubmed/33130397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.103067
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