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Negative autoregulation of BMP dependent transcription by SIN3B splicing reveals a role for RBM39
BMP signalling is negatively autoregulated by several genes including SMAD6, Noggin and Gremlin, and autoregulators are possible targets for enhancing BMP signalling in disorders such as fibrosis and pulmonary hypertension. To identify novel negative regulators of BMP signalling, we used siRNA scree...
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| Опубликовано в: : | Sci Rep |
|---|---|
| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4914931/ https://ncbi.nlm.nih.gov/pubmed/27324164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28210 |
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