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Negative autoregulation of BMP dependent transcription by SIN3B splicing reveals a role for RBM39
BMP signalling is negatively autoregulated by several genes including SMAD6, Noggin and Gremlin, and autoregulators are possible targets for enhancing BMP signalling in disorders such as fibrosis and pulmonary hypertension. To identify novel negative regulators of BMP signalling, we used siRNA scree...
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Publicado en: | Sci Rep |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado: |
Nature Publishing Group
2016
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4914931/ https://ncbi.nlm.nih.gov/pubmed/27324164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28210 |
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