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Phosphoinositide 3-Kinase Delta Regulates Dectin-2 Signaling and the Generation of Th2 and Th17 Immunity
The C-type lectin receptor (CLR) Dectin-2 can trigger the leukotriene C(4) synthase (LTC(4)S)-dependent generation of cysteinyl leukotrienes (cys-LTs) and the CARD9- and NF-κB-dependent generation of cytokines, such as IL-23, IL-6, and TNF-α, to promote Th2 and Th17 immunity, respectively. Dectin-2...
Guardat en:
| Publicat a: | J Immunol |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4912906/ https://ncbi.nlm.nih.gov/pubmed/27194783 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502485 |
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