Dectin-2 Deficiency Promotes Th2 Response and Mucin Production in the Lungs after Pulmonary Infection with Cryptococcus neoformans

Dectin-2 is a C-type lectin receptor that recognizes high mannose polysaccharides. Cryptococcus neoformans, a yeast-form fungal pathogen, is rich in polysaccharides in its cell wall and capsule. In the present study, we analyzed the role of Dectin-2 in the host defense against C. neoformans infectio...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Nakamura, Yuri, Sato, Ko, Yamamoto, Hideki, Matsumura, Kana, Matsumoto, Ikumi, Nomura, Toshiki, Miyasaka, Tomomitsu, Ishii, Keiko, Kanno, Emi, Tachi, Masahiro, Yamasaki, Sho, Saijo, Shinobu, Iwakura, Yoichiro, Kawakami, Kazuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294247/
https://ncbi.nlm.nih.gov/pubmed/25422263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02835-14
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